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WHAT IS OZONE?

a flower in the hand
water bubbles
a hand with the sun
Ozone is a gas that, carefully dosed, is a natural medicine with no contraindications. Is one of the most studied molecules, both in the medical and industrial field. It can be used in many human activities, animals, and plants improving at no cost the quality and the health. The Ozone is the triatomic molecule of oxygen whose the chemical formula is O3. Is generated by a silent electric discharge in an alternating field of high voltage (corona discharge). The discharge cleaves a part of the oxygen molecules that electrify the discharge zone. The oxygen atoms, made available, combine with other molecules oxygen to form triatomic oxygen, ozone. To atmospheric pressure is a blue gas, with a pungent smell perceptible in a minimum quantity of around 0.05 ppm. Ozone is an unstable gas which the effect during few minutes before backing into oxygen, that’s why it must be produced at the time to use. The gas protects the inhabitants of the earth against the ultra-violet radiation and is one of the most powerful oxidants in nature ( only second to fluorine). It is also the most effective bactericidal and virucidal existing on earth and is used to destroy algae, mushrooms, pesticides, heavy metals, nitrates, nitrites, etc.. Despite being an element known since the nineteenth century, only in 90’s years it has arrived at its mechanisms purposes of action in the medical field with a great success in the oxygen-ozone therapy.

In July 1996 Protocol. 24482, the Ministry of Health has recognized the ozone as a “Method of sterilization for natural environments.” The industry has grown very rapidly especially in the recent years, in particular in healthcare(hospitals, nursing homes, shopping centre well-being), livestock, food processing, military and Civil (sanitizing of homes, offices, and gyms). So the ozone breaks down completely viruses, bacteria, moulds, and spores, causing the mass of protein bacterial a process of catalytic oxidation, very different from that of chlorine, that is very harmful to the human body. Contrary to chlorine and various chlorine derivatives, ozone acts not only on bacteria but also on viruses and spores. The germicidal action of ozone is based on its high capacity to direct oxidation; thanks to this quality all macromolecular structures of microbial cell and not (mould, mushrooms, yeasts, algae, etc..) are deeply altered and inactivated. There are no microbial species that can resists even if it produces spore or cysts. In each case, the germicidal action is rapid, complete and without secondary appreciable residues. With the gas, use can be obtained, in the prevention of water contamination by Legionella and by many other species of bacteria resistant to chlorine, excellent results. The germicidal action of ozone is not influenced by pH changes as well as it is not influenced, except in small measure, by the simultaneous presence of organic and inorganic substances. About the virucidal action it is interesting to note that, with a small percentage of ozone (0.3 ppm) and with a contact time of 4 minutes, the rate of virus inactivation reaches the 99%.

OZONE HISTORY

Evaluation of the anti-bacterial and epithelization olive oil ozonated

The studies on substances that yield oxygen used in medicine to bactericidal purpose are known since the discovery of hydrogen oxides made by Thenard in 1818. At that time, In the pharmaceutical practice, inorganic and organic peroxides were used, while the ozone, which is 1885 Schonbein and others recognized the benefits, was used in the medical field for the first time by Knox in 1914 in the form of ozonated oil. The first research on the lethal effects of ozone on microbes (used in the form of ozonated olive oil) is reported by Harada and Stevens in 1934, while in 1936 Bender writes about the possibility to use ozone clinically. Research by Cronheim then pointed out the bactericide and fungicide effects of ozonated olive oil on different strains.

In the ’50s it was considered the possibility of using the ozonated olive oil in the medical field on a large scale; the ozonated olive oil was used in the US and was on the market in the form of fluid oil with disinfectant and regenerative effects on the wounds; however, it was later taken off the market because of easy decomposability. They have then produced substances with greater consistency, which maintain their effect over the years. This has reignited the interest from pharmacology and therefore the use of ozonated olive oil could regain considerable space. Gaseous ozone is going to link to the double bonds of the unsaturated fatty chains in olive oil. Through an electrophilic addition reaction allows incorporation of 3 Ozone oxygen atoms in the double bond; the higher the level of unsaturation, the higher the amount of oxygen that can be “stored”.